教师

The impact of racial, 少数民族, and gender disadvantage on maternal, child and family health in urban United States and the Middle East.

Multimodality neuromonitoring, advanced neurophysiologic monitoring, intensive insulin therapy for SAH, IV and IA thrombolysis for acute ischemic strokes, Moderate hypothermia

Emergency Medicine; Toxicology; Medical Education

Effect of drug metabolism on adverse drug reactions

Clinical trials in Breast Cancer

Dr. Licinio's work has examined the link between obesity and depression, looking into how anti-depressants can cause weight gain. Most recently, he co-led, with Dr. 马力的黄, a study with a team of international researchers providing evidence of a strong link between schizophrenia and the organisms that reside in the digestive tract. The team found through genetic sequencing, vast differences of the gut microbiomes found in those with schizophrenia. These findings could transform the way schizophrenia is treated. He is also founder and current editor-in-chief of Molecular Psychiatry.

Julio Licinio , MD/PhD CV

Intraop neuromonitoring, neuroprotection, brain ischemic injury and introperative fluid managmeent

Neural circuit mechanisms of feeding regulation in Drosophila

Dr. Liu’s laboratory is studying how genetic variants impact gene expression, protein abundance and various levels of regulatory networks, ultimate influence the risks of developing major psychiatric disorders, treatment responses, as well as related psychological, 行为特征. 由NIH资助, his current projects are about regulatory networks in genomics, 表观基因组学, and proteomics of postmortem brains. Multiple advanced sequencing-based technologies, cell biology and bioinformatics methods are commonly used in this lab to facilitate discovery of risk genes and pathways.

Chunyu Liu , PhD CV

• Endothelial dysfunction in coronary artery disease
• Lipotoxicity/glucotoxicity and endothelial/myocyte dysfunction in diabetes
• Clinical and genetic analysis of valve diseases/Strain/strain rate imagine in cardiomyopathy

Development of lipid nanoparticles for the delivery of small molecule drugs, 蛋白质, and DNA/RNA for gene therapy, cancer immunotherapy, 信使核糖核酸疫苗, 等.

Endovascular strategies to improve outcome in stroke, complex aneurysms and AVM/AVF. Endothelium and blood clot interaction and role of vasodilarot in stroke therapy

Protein engineering, design, and folding

• Nuclear receptors in regulation of hepatic gene expression and liver diseases
• Progression of alcoholic/non-alcoholic fatty liver to steatohepatitis, 肝硬化, 还有肝癌
• Development of liver-targeting prodrugs and liver-specific  delivery of genes/蛋白质
• Liver-lung-dual-specific mRNA delivery for the treatment of ARDS and sepsis

纳米, 药物输送, cancer imaging and cancer treatment; gene delivery and gene therapy, protein/peptide delivery. biomaterials in tissue engineering; combinatorial chemistry and drug discovery; High throughput screening; microarrays.